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Photoaffinity probes
Photoaffinity Probes Specialized biochemical tools used in molecular biology and drug discovery to study the interactions between a target molecule (such as a protein) and a small molecule or ligand (mainly non-covalent).Widely used in active small molecule target discovery, off-target protein identification and distribution imaging. Many active small molecule compounds, such as metabolites, natural products, and drug molecules, interact dynamically and reversibly with target proteins in... -
Bioorthogonal Chemical Probes
Bioorthogonal chemical probes Specialized tools used in chemical biology to study and manipulate biological processes within living systems without interfering with the native biochemical processes. Usually designed to perform specific chemical reactions that are both highly selective and inert to the plethora of chemical activities occurring in cells. The reactivity of amino acid residues in proteins plays a crucial role in protein function regulation and drug development. Taking cysteine as...
