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Chemical Proteomics
Platform
DIA-ABPP
Chemoproteomic Profiling of Bioactive Molecule’s Targets in Phenotype-Related Systems
Product
Chemical Probe
Photoaffinity probes
Bioorthogonal Chemical Probes
Kits & Beads
Bioorthogonal Coupling Reaction Kit
ChomiX-Magbeads Streptavidin (SA) Coated Magnetic Beads
Chomix -Agaroseresins Azide Resin, Acid Cleavable Linker Group
Pre-clinical Pipeline
AutoProtChemix
Automated Chemoproteomic Workstation
Service
Drug Discovery
Chemoproteomic Discovery of Covalent Small Molecule Ligands for Undruggable Targets in Living Cells
Drug Target Identification
Identification of non-covalent small molecule drug targets based on photoaffinity probes
Identification of the binding site for non-covalent small molecule drugs in living cells
Identification of Non-covalent Small Molecule Drug Targets Based on Photoaffinity Magnetic Beads
Identification of Small Molecule Drug Targets Based on Thermal Proteome Profiling
Quantitative Analysis of Occupancy and Selectivity of Covalent Small Molecule Drug Targets
Target Identification and Selectivity Analysis of Targeted Protein Degraders
Protein Interactome Identification
Identification of Protein-Protein Interaction in Living Cells: Proximity Labeling
Identification of Protein-Protein, Antibody-Antigen Interaction Regions: Chemical Cross-Linking
Protein PTMs Analysis
Cysteine Post-Translational Modifications Omics Analysis
Lysine Post-Translational Modifications
Serine/Threonine Post-Translational Modifications
Proteomic Service
Protein Qualitative/Quantitative Analysis
Targeted Proteomics Analysis
Protein Absolute Quantification Analysis
Resource
Press Releases
Events
Case Study
ABPP-Itaconate
Quantitative Analysis of Occupancy and Selectivity of Covalent Small Molecule Drug Targets
ABPP – Berberine
Chemical Proteomics: Cisplatin
Protein Absolute Quantification Analysis
Proximity Labeling Strategy: PLGPB
Chemical Proteomics – SLC15A4
Chemical Proteomics: New Targets for Natural Products
Small Molecule WA: PHGDH Enzyme Regulation
Metal-Binding Proteins: METAL-TPP
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Probe
Photoaffinity probes
Photoaffinity Probes Specialized biochemical tools used in molecular biology and drug discovery to study the interactions between a target molecule (such as a protein) and a small molecule or ligand (mainly non-covalent).Widely used in active small molecule target discovery, off-target protein identification and distribution imaging. Many active small molecule compounds, such as metabolites, natural products, and drug molecules, interact dynamically and reversibly with target proteins in...
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Bioorthogonal Chemical Probes
Bioorthogonal chemical probes Specialized tools used in chemical biology to study and manipulate biological processes within living systems without interfering with the native biochemical processes. Usually designed to perform specific chemical reactions that are both highly selective and inert to the plethora of chemical activities occurring in cells. The reactivity of amino acid residues in proteins plays a crucial role in protein function regulation and drug development. Taking cystei...
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